Epigenetic Cancer Therapy

<i>Epigenetic Cancer Therapy, Second Edition</i> provides a comprehensive discussion of healthy and aberrant epigenetic biology, and the potential new discoveries hold to improve our understanding of cancer epigenetics and therapeutics. The book encompasses both large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically. Increasing evidence links pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes