Early Detection In Alzheimer'S Disease

<i>Early Detection of Alzheimer''s Disease: Biological and Technological Advances</i> aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer''s Association, 5.8 million Americans are living with Alzheimer''s and care costs will cost the nation approximately $290 billion (2019 Alzheimer''s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of sy